Projects
Department of Biological Sciences
Projects
| Title | PI/Co-PI/Scholar | Funding Type / Agency | Period Support | Duration (In Years) | Status |
|---|---|---|---|---|---|
| Unraveling the molecular mechanisms of Bacteriophage Defense against CRISPR Cas and other Bacterial immune systems | Dr Sutharsan Govindarajan, Barath S | Govt DST INSPIRE Fellowship |
2023-2028 | 5 | On Going |
| Targeting Kennedy pathway of cellular phosphatidylethanolamine biosynthesis as a common therapeutic strategy against protozoan parasites like Leishmania donovani, Trypanosoma brucei and Entamoeba histolytica | Dr Writoban Basu Ball | Govt DST-SERB SRG |
2021-2023 | 2 | On Going |
| Mechanistic understanding of bacterial cytoskeleton inhibition by antibiotics and novel bacteriophage proteins | Dr Sutharsan Govindarajan | Govt DST-SERB |
2021-2024 | 3 | Completed |
| Jumbo-phage as a model for ancient cell organization | Dr Sutharsan Govindarajan | Govt DBT-Wellcome Trust |
2020-2025 | 5 | Completed |
| Designing of RNA structure-guided antisense oligonucleotides to rescue SMN2 splicing for developing an indigenous therapy against spinal muscular atrophy | Dr Kaushik Saha, Ramya R | Govt ICMR |
2025-2028 | 2 | Ongoing |
| Building a Collaborative Network to Conduct a Comparative Study on Antimicrobial Use and Resistance in Apparently Healthy Populations Across Multiple Regions in India | Dr Jayaseelan Murugaiyan | Sponsoring Agency The Academy of Medical Sciences, UK |
2024-2025 | 1 | Completed |
| Novel circulating protein fingerprints for therapeutic monitoring of lymphoedema reversal following the integrative treatment | Dr Jayaseelan Murugaiyan | Sponsoring Agency Institute of Applied Dermatology (IAD), Karasargod, Kerala |
2024-2025 | 1 | Completed |
| Comprehensive antimicrobial resistance (AMR) profiling of ESKAPE pathogen Acinetobacter baumannii isolated from environment, veterinary, and humans in Mangalagiri mandal, Andhra Pradesh | Dr Jayaseelan Murugaiyan | Govt DST-SERB |
2023-2026 | 3 | On Going |
| Understanding the molecular basis for the extreme differential level of expression of genes from human and animal rotaviruses in gene-transfected cells: Implications for improving the growth of human vaccine strains | Dr C Durga Rao | Govt DBT |
2021-2024 | 3 | Completed |
| Molecular investigation of Cas3-based CRISPR-Cas functions and novel anti-phage mechanisms in Pseudomonas aeruginosa | Dr Sutharsan Govindarajan, Nandhakumar M | Govt CSIR-Direct SRF |
2025-2027 | 2 | Ongoing |
| From Milk To Mind: Milk-Derived Extracellular Vesicles As A Novel Therapeutics For Addressing Anxiety-Related Behaviour | Dr Yenuganti Vengala Rao | Govt ANRF-NPDF |
2025-2027 | 2 | On Going |
| Milk-Derived Extracellular Vesicles as Bioactive Supplements to Enhance Gut Microbiota and Cognitive Development in Formula-Fed Neonatal Mice. | Dr Yenuganti Vengala Rao | Govt ANRF-ECRG |
2026-2029 | 3 | On Going |
| Self-therapeutic, self-regulating, CD44-targeting and inflammation-responsive polymeric nanoparticles to restore redox homeostasis in age-related macular degeneration. | Dr Chiranjeevi Korupalli | Govt ANRF-ECRG |
2026-2029 | 3 | On Going |
| Pilot-scale ultra-efficient fixative sewage dye-degradation by “3D mega catalyst” generated using intact eggshell-waste | Prof. Anil K Suresh | Govt DBT |
2022-2024 | 2 | Completed |
| Genomic Surveillance-Driven Phage Therapy: A Bench-to-Bedside Approach Against Drug-Resistant pathogens | Dr Sutharsan Govindarajan | Sponsoring Agency SreePVF |
2026-2029 | 3 | On Going |
| Decoding bacteriophage nucleus-like compartments and their evolution | Dr Sutharsan Govindarajan | Govt DBT |
2026-2029 | 3 | On Going |
| Understanding the genetic bases, dissemination and evolution of plasmid mediated phage resistance | Dr Sutharsan Govindarajan | Govt Indo-French Centre for the Promotion of Advanced Research (CEFIPRA) |
2026-2029 | 3 | On Going |
| Examining sialic acid cleavage, uptake, and its role in molecular mimicry and host attachment by Acinetobacter baumanii to modify therapeutic targets in host-pathogen interactions | Dr Sudeshna Saha, Dr Kaushik Saha | Govt ICMR |
2026-2029 | 3 | On Going |
| CRISPR/Cas-Mediated Editing of Cis-Regulatory Elements to Increase Beta-Carotene content in Tomato | Dr Prateek Gupta | Govt ANRF - ECRG |
2026-2028 | 2 | On Going |
| Genetic Dissection and Functional Validation of Carotenoid and Soluble Solids Content in Tomato Using Mapping-by-Sequencing and CRISPR/Cas9 | Dr Prateek Gupta | Govt ANRF - ARG |
2026-2030 | 4 | On Going |